SARS-CoV-2 reinfection likely without vaccination
SARS-CoV-2 reinfection likely without vaccination
Researchers from Yale School of Public Health and Temple University joined forces provided the first estimates of the expected probability of infection given IgG antibody levels to the spike protein for SARS-CoV-2, as well as for SARS-CoV, MERS-CoV, and the endemic coronaviruses HCoV-229E, HCoV-HKU1, HCoV-OC43, and HCoV-NL63, under endemic conditions. The article was published in The Lancet (DOI: 10.1016/S2666-5247(21)00219-6). By characterizing the typical waning profile over time for IgG antibody levels to the spike protein, nucleocapsid protein, and to the whole viral lysate, Dr. Jeffrey Townsend and collaborators derived the corresponding probabilities of SARS-CoV-2 reinfection that provide a timeframe crucial to numerous aspects of public health decision making. Their findings indicate that reinfection after natural recovery from COVID-19 will become increasingly common as the pandemic progresses.
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